Healthcare AI
June 27, 2024

Accelerating Healthcare Innovation using AI Solutions with Raja Shankar, VP of Machine Learning at IQVIA

Raja Shankar, VP of Machine Learning at IQVIA, explores AI's impact on healthcare and pharma, from accelerating drug discovery to enhancing productivity.
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TLDR:

  • Early stages of AI in drug discovery show promise in finding new indications and designing molecules.
  • AI boosts productivity in clinical trials by automating data processing, document preparation, and protocol generation, allowing for acceleration of drug development timelines.
  • Clinical decision support benefits from AI's ability to predict treatment responses and improve patient outcomes.
  • AI can automate administrative tasks such as prior authorizations and medical triage, reducing healthcare costs and improving efficiency.
  • Organizations must strategically decide between building in-house AI capabilities vs external vendor partnerships.

Before we dive into the key takeaways from this episode, be sure to catch the full episode here:

Meet Raja — A Machine Learning Master in Healthcare

Raja Shankar, the Vice President of Machine Learning at IQVIA, brings a wealth of experience from his time at the World Bank and Boston Consulting Group before diving into the AI realm.

Raja's journey, spanning years in strategy consulting and now AI in healthcare, offers a unique perspective into the challenges and opportunities AI presents for healthcare and pharmaceutical professionals. He examines the evolutionary trajectory of AI’s impact on these industries and what the future holds.

The Journey of AI in Drug Discovery

Current State and Early Promises

Raja emphasizes that AI's role in drug discovery is still in its infancy, but the potential is staggering. AI is making strides in finding new indications for existing drugs and matching molecules to biological targets. However, we're still far from seeing AI-driven end-to-end drug discovery.

“I think we are still at the early stages of using AI for drug discovery. There has been a lot of talk about this, especially in terms of using AI to find new indications for existing assets or matching molecules to biological targets to ensure that we find the right matches, both in terms of efficacy and safety.”
- Raja Shankar

The Rise of Generative AI

The real game-changer, according to Raja, is generative AI in drug discovery. While designing new molecules remains challenging, the potential for AI to revolutionize this process is immense. Generative AI could potentially design entirely new molecules, opening up unprecedented possibilities in pharmaceutical research.

Enhancing Productivity in Healthcare and Pharma

Automating Documentation and Analysis

AI is set to dramatically improve productivity in healthcare and pharmaceutical processes. Raja points out several areas ready for AI-driven enhancement, including automating document preparation, streamlining clinical trial design, and expediting regulatory submissions. This could lead to significant time reductions and quality improvements in critical processes.

Revolutionizing Healthcare Services

Raja envisions a healthcare system where AI-powered solutions can significantly improve patient experience and reduce costs. From automating triage processes to providing immediate responses to patient queries, AI could transform how healthcare services are delivered, making them more efficient and accessible.

The Promise of AI in Clinical Decision Support

Enhancing Treatment Choices

Raja's excitement is evident when discussing AI in clinical decision support. AI's ability to predict treatment responses and disease progression by analyzing vast amounts of data could lead to more accurate diagnoses and personalized treatment plans. This could potentially improve patient outcomes by providing physicians with data-driven insights.

Overcoming Human Limitations

The power of AI in healthcare lies in its ability to process and analyze enormous datasets, augmenting human capabilities rather than replacing them. Raja emphasizes that it's about giving healthcare professionals tools to make more informed decisions, not about replacing human judgment.

Challenges in AI Adoption

Data Integration and Expertise

Raja doesn't shy away from the challenges. Integrating diverse data sources and finding the right blend of AI capabilities and human judgment is complex and requires skill and patience. He highlights the need for domain expertise in effectively implementing AI solutions.

"You need to do the prompt engineering to be able to do it. But that prompt engineering or the prompting actually requires domain expertise. If you do not know what document you want or what section you want to write, you will not be able to provide the right prompt or the right question."
- Raja Shankar

Organizational and Cultural Barriers

The biggest hurdle, according to Raja, is organizational resistance to change. Balancing innovation with established processes is a significant challenge in these traditional industries. He stresses the importance of getting buy-in from all levels of the organization for successful AI implementation.

Strategies for Successful AI Implementation

Balancing Centralization and Innovation

Raja advises a balanced approach to AI implementation, maintaining centralized governance while allowing for decentralized experimentation to foster innovation. This approach allows for quick wins while still working towards long-term, transformative projects.

The Vendor Ecosystem

Choosing the right AI partners is crucial. Raja suggests a strategic approach to selecting and integrating various AI solutions and providers, considering factors like infrastructure, foundation models, and specific applications. It is important to understand both the technology and the specific needs of the healthcare and pharmaceutical industries.

The Future Landscape of AI in Healthcare and Pharma

Drivers of Innovation

Raja sees smaller, more agile companies as potential leaders in AI adoption, able to innovate quickly in ways that larger companies might struggle with. These companies might be able to leverage AI to launch drugs and services with fewer resources than traditional methods. They may be more willing to take risks and experiment with cutting-edge AI technologies.

Pressure on Established Players

Larger healthcare and pharma companies are feeling the pressure to adapt. Raja points out that embracing AI is becoming necessary to remain competitive and efficient, particularly in the face of increasing competition and pressure from payers. He suggests that these companies need to find ways to incorporate AI into their existing processes to stay relevant.

Ethical and Regulatory Considerations

Raja emphasizes that while legal and compliance issues exist, they're not insurmountable. He sees an opportunity for a more robust understanding of AI's potential as younger, tech-savvy individuals join regulatory bodies. Raja urges proactive engagement with regulators to shape the future of AI governance in the industry, emphasizing the importance of addressing issues like bias, hallucination, security, and IP protection.

Conclusion

As healthcare and pharmaceuticals continue to evolve, the impact of AI will become increasingly significant. Raja Shankar's insights highlight the need for a holistic approach, balancing human expertise with AI capabilities, and navigating regulatory concerns. By embracing AI's potential while addressing its risks, these industries can create a more efficient, transparent, and patient-centric future, where technology augments human capabilities to improve health outcomes. The journey ahead is challenging but filled with immense possibilities for those willing to innovate and adapt.

Want to learn more about AI in healthcare? Check out this episode on how AI enables personalized healthcare for better outcomes with Jayodita Sanghvi.

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